Biophysical Characterisation Facility
While the availability of whole genome sequences has given biologists an understanding of the building blocks for a wide range of organisms, the next major task is to decipher how these parts are formed and how they interact with each other to form a functioning organism.
City East's Biophysical Characterisation Facility (BCF) is helping keep South Australia at the cutting edge of the post-genomic research landscape by allowing scientists to study proteins quantitatively at a biophysical level.
The BCF houses a collection of state-of-the-art equipment previously unavailable at one location in SA, including a CD spectrometer, isothermal calorimeter and Biacore TX100.
The equipment allows scientists to examine protein-protein interactions; protein structure, function and stability; kinetic and thermodynamic properties of protein-protein and protein-drug interactions; as well as the molecular interactions of compounds.
It is this kind of research that is essential, not only to better understand disease and develop innovative new drugs, but also to shed light on the basis behind disease and medicines interaction.
Managed by Dr Emma Parkinson-Lawrence, the BCF is a cooperative venture involving UniSA, the University of Adelaide, the Institute of Medical and Veterinary Science, the Women's and Children's Hospital, and AIB Labs.
Dr Emma Parkinson Lawrence - facility manager
The BCF advisory board includes representatives from UniSA, University of Adelaide and meets throughout the year to review progress and recommend strategic initiatives.
Management group members include:
The BCF enjoys productive relationships with a number of collaborators and clients including:
- University of Adelaide
- Hanson Institute (SA Pathology)
- IMVS (SA Pathology)
- John Hopwood - Women's and Children's Hospital (SA Pathology)
- Centre for Pharmaceutical Innovation and Development (UniSA)
The BCF offers access to the equipment for publicly funded researchers as well as offering contract research services to industry.
For more information about the Biophysical Characterisation Facility, please email Emma Parkinson-Lawrence.
Areas of study and research
- Health Research
- Alliance for Research in Exercise, Nutrition and Activity (ARENA)
- Centre for Cancer Biology
- Centre for Drug Discovery and Development
- Centre for Population Health Research
- Centre of Research Excellence for the Prevention of Chronic Conditions in Rural and Remote High Risk Populations
- International Centre for Allied Health Evidence
- Medicine and Device Surveillance CRE
- Quality Use of Medicines and Pharmacy Research Centre
and Social Sciences
- Art, Architecture and Design
- Communication, International Studies and Languages
- Psychology, Social Work and Social Policy
- Hawke Research Institute
- Asia Pacific Centre for Work Health and Safety
- Australian Centre for Child Protection
- Barbara Hardy Institute
- Centre for Research in Education
- Hawke EU Jean Monnet Centre of Excellence
- Centre for Islamic Thought and Education
- International Centre for Muslim and non-Muslim Understanding
- Research Centre for Languages and Cultures
- Zero Waste SA Research Centre for Sustainable Design and Behaviour (sd+b)
IT, Engineering and
- Future Industries Institute
- UniSA College