Centre for Drug Formulation and Delivery
The
Centre for Drug Formulation and Delivery (CDF&D) is an educational, research
and pharmaceutical production facility based at UniSA's Sansom Institute for
Health Research. It is part of the Institute's Therapeutics and
Pharmaceutical Science research concentration.
Established in 2007, the CDF&D aims to harness South Australia's
pharmaceutical science expertise to become a world leader in the development
of novel drug delivery technologies.
The Centre boasts a new purpose-built laboratory with pilot-scale
pharmaceutical manufacturing equipment that provides UniSA researchers and
Bachelor of Pharmaceutical
Science students access to state-of-the-art facilities to match industry
standards.
With support from government and the pharmaceutical and biotechnology
sectors, the CDFD is involved in collaborative projects, developing new
products technologies with the ultimate aim of improving human health.
People
Projects
Collaborators
Publications
Contract services
Contact
People
Key staff
Dr May Song - formulation scientist
Frank Peddie - adjunct senior research fellow
Professor Allan Evans - PVC and senior advisor
Professor Michael Roberts - consultant
Associate Professor Bob Milne - consultant
Dr Des Williams - consultant
Dr Andrew Davey - consultant
Postgraduate students
Shasha Rao
CDFD advisory board
The CDFD advisory board - which includes representatives from UniSA's Sansom
Institute and Ian Wark Research Institute, the Royal Adelaide Hospital and
the pharmaceutical industry - meets three times a year to review progress
and recommend strategic initiatives.
Advisory board members include:
- Dr May Song
- Frank Peddie
- Professor Allan Evans
- Professor Michael Roberts
- Associate Professor Bob Milne
- Professor Ross McKinnon
- Dr Des Williams
- Dr Jiping Wang
- Dr Andrew Davey
- Dr David Foster
- Rachael Penning-Bourne
Industry representatives:
- Keith Smith (Virient P/L)
- Kellie La Fontaine (PharmaQest)
- Angelo Morella (Mayne Pharma International).
Projects
The CDFD is involved in various University, government and industry-funded
projects aimed at developing better pharmaceutical products and drug
delivery technologies.
Some of our current projects include:
- A controlled release injection for an anticancer drug
- A controlled release tablet for asthma treatment
- Controlled release pellets (for Biotechnologies Pty Ltd)
- A controlled release injection (for Quantec Limited, New Zealand)
- Buccal patch technology for drug delivery
- Proliposome delivery systems for oral administration of poorly soluble drugs
- In vivo study of novel oral formulations of a model drug (indomethacin).
Collaborators
The CDFD enjoys productive relationships with a number of collaborators and clients including:
- Quantec Limited (New Zealand)
- Biotechnologies Pty Ltd
- The Ian Wark Research Institute (UniSA)
- CPR (UniSA)
- PharmaQest Pty Ltd (UniSA spin-off company)
- Mayne Pharma International
- Metabolic Pharmaceuticals Pty Ltd
- Acrux Limited
- Sigma Tau (USA)
Recent publications
CDFD researchers are indicated in bold
1. Jie Zhuang,Qineng Ping, Yunmei Song,Jianping Qi, Zheng
Cui, Effects of chitosan coating on physical properties and pharmacokinetic
behaviour of mitoxantrone liposomes. International Journal of Nanomedicine.
2010, 5: 407-416;
2. Spomenka Simovic, He Hui, Yunmei Song, Andrew K. Davey,
Thomas Rades, Clive A. Prestidge, An oral delivery system for indomethicin
engineered from cationic lipid emulsions and silica nanoparticles, Journal
of Controlled Release. 2010, 143:367-373;
3.Jianping Qi, Minjie Sun, Qineng Ping, Jie Zhuang, Jiangran Li,
Frank Peddie, Yunmei Song. The mechanisms for
enhanced oral absorption of hydroxysafflor yellow a by chuanxiong volatile
oil. Planta Medica. 2010, 76(8):786-92;
4. Spomenka Simovic, Peter Heard, He Hui, Yunmei Song,
Frank Peddie, Andrew Davey,
Andrew Lewis and Clive A. Prestidge. Dry hybrid capsules engineered from
submicron lipid droplets and nanoparticles. Mol Pharm. 2009, 6(3):861-72;
5. Yunmei Song, Jie Zhuang, Yanyu Xiao, Qineng Ping.
Preparation of silybin-phospholipid complex and study on its properties.
Pharmazie. 2008, 63(1):35-42;
6. Prestidge, CA, Barnes, TJ,
Mierczynska-Vasilev, A, Kempson, I, Peddie, F and Barnett,
C, 'Peptide and protein loading into porous silicon wafers' Phys. Stat. Sol.
(a), 2008, 205(2), 311-315;
7. Prestidge CA,
Barnes TJ, Mierczynska-Vasilev
A, Skinner W, Peddie F, Lau CH and Barnett C, Loading and
release of a model protein from porous silicon powders Phys. Stat. Sol. (a),
2007,204(10), 3361-3366.
Contract services
The CDFD offers contract research and development services (particularly in
drug formulation and development), with specific expertise in:
1. Formulation development and preparation of novel systems for delivering
active substances (Applications may include human pharmaceutical or
veterinary use, and also controlled release of gases, chemicals or other
agents into a wide range of environments.)
2. Drug quality evaluations, including in vitro and in vivo studies
3. In-vivo animal toxicity trials, pharmacokinetic and pharmacodynamic
studies
4. Analytical services
5. In-vivo Phase I & II clinical trials (in conjunction with the CPR)
6. Collaborative R&D with access to government funding schemes (e.g. ARC
Linkage or NH&MRC Grants, AusIndustry Commercial Ready Grants for Industry.)
Contact
For more information on the Centre for Drug Formulation and Delivery, please
contact
May Song on:
phone: +61 8 8302 2429
fax: +61 8 8302 1087
email: may.song@unisa.edu.au
