- Podcast: Creating standard methodology in the field of nanomedicine
A significant barrier to progress in the multidisciplinary area of nanomedicines is the variability of published literature with regards to characterizations performed and experimental details reported.
A team of researchers including Professor Clive Prestidge from UniSA's School of Pharmacy and Medical Sciences looked into how they can create a standard methodology in this field.
Article: Minimum information reporting in bio-nano experimental literature
Authors: Matthew Faria, Mattias Björnmalm, Kristofer J. Thurecht, Stephen J. Kent, Robert G. Parton, Maria Kavallaris, Angus P. R. Johnston, J. Justin Gooding, Simon R. Corrie, Ben J. Boyd, Pall Thordarson, Andrew K. Whittaker, Molly M. Stevens, Clive A. Prestidge, Christopher J. H. Porter, Wolfgang J. Parak, Thomas P. Davis, Edmund J. Crampin & Frank Caruso
Published in: Nature Nanotechnology September 2018
- Podcast: What drives the obesity epidemic?
Obesity is a major health issue in the developed and developing world, and is in part due to excess dietary energy intake. A new study showed that increased fat content alone was associated with increased energy intake and adiposity, suggesting that the availability of high-fat foods might be driving the development of overweight or obesity.
Article: Availability of high-fat foods might drive the obesity epidemic
Authors: Jonathan Buckley
Published in: Nature Reviews Endocrinology September 2018
- Podcast: China's response to a national land-system sustainability emergency
Professor Jeff Connor and a team of researchers reviewed 16 sustainability programmes, which invested US$378.5 billion (in 2015 US$), covered 623.9 million hectares of land and involved over 500 million people, mostly since 1998.
Article: China’s response to a national landsystem sustainability emergency;
Authors: Brett A. Bryan, Lei Gao, Yanqiong Ye, Xiufeng Sun, Jeffery D. Connor, Neville D. Crossman, Mark Stafford-Smith, Jianguo Wu, Chunyang He, Deyong Yu, Zhifeng Liu, Ang Li, Qingxu Huang, Hai Ren, Xiangzheng Deng, Hua Zheng, Jianming Niu, Guodong Han & Xiangyang Hou
Published in: Nature July 2018
- Podcast: How melanoma evolves
In this recently published paper in the magazine “Cancer Cell”, Professor Tarl Prow and a team of researchers study the transition of a nevus into a melanoma and then beyond into a metastatic melanoma.
Article: Genomic and Transcriptomic Analysis Reveals Incremental Disruption of Key Signaling Pathways during Melanoma Evolution;
Authors: A. Hunter Shain, Nancy M. Joseph, Richard Yu, Jamal Benhamida, Shanshan Liu, Tarl Prow, Beth Ruben, Jeffrey North, Laura Pincus, Iwei Yeh, Robert Judson, Boris C.
Published in: Cancer Cell, July 2018
- Podcast: Acute myeloid leukemia
In this podcast, UniSA’s Professor Richard D’Andrea and Professor Scott Hamish discuss their latest findings in regards to acute myeloid leukemia published in their article: ‘Differential effects on gene transcription and hematopoietic differentiation correlate with GATA2 mutant disease phenotypes’
Authors: C-E Chong, P Venugopal, PH Stokes, YK Lee, PJ Brautigan, DTO Yeung, M Babic, GA Engler, SW Lane, M Klingler-Hoffmann, JM Matthews, RJ D'Andrea, AL Brown, CN Hahn and HS Scott
Published in: Leukemia, March 2018
- Podcast: Association of statin exposure with histologically confirmed IIM.
Statin medications reduce low density lipoprotein (LDL cholesterol) to reduce the risk of cardiovascular disease and are one of the most commonly prescribed medications world-wide. They are highly effective and are generally well tolerated by most patients. There are potential side-effects including the well-known muscle adverse effects such as muscle pain and weakness. Idiopathic inflammatory myositis is a group of very rare, clinically diverse autoimmune muscle disorders that can be severe and debilitating which may be associated with statin use. In this population-based case control study of 221 patients with idiopathic inflammatory myositis we observed a 79% increased likelihood of statin use in patients with idiopathic inflammatory myositis compared with controls (people without the condition). While we cannot conclude a causative role from our observed association, the results of this study highlight the need for an increased awareness and recognition of this potential rare adverse effect associated with statin use.
Article: Association of Statin Exposure With Histologically Confirmed Idiopathic Inflammatory Myositis in an Australian Population
Authors: Gillian E. Caughey, PhD; Genevieve M. Gabb, MBBS, MPH; Saffron Ronson, BPharm (Hons); Michael Ward, PhD; Timothy Beukelman, MD, MSCE; Catherine L. Hill, MBBS; Vidya Limaye, MBBS, PhD
Published in: JAMA Internal Medicine
- Podcast: Psychological micro-targeting: do we know if it works?
With all the buzz and hysteria about how consumers are being connivingly “micro-targeted” in a bid for mind control, not only by advertisers of products but also by political parties, researchers at UniSA’s Ehrenberg-Bass Institute for Marketing Science have discovered there is probably no reason to panic.
Personalised advertising may be one thing but getting people to respond to even micro-targeted ads is a whole other ball game.
Professor Byron Sharp, Director of the Ehrenberg-Bass Institute chats to Paul Willis about his recent paper, co-written with colleagues from the Institute : Psychological micro-targeting: do we know if it works?
Article: Psychological micro-targeting: do we know if it works?
Authors: Professor Byron Sharp, Dr. Nick Danenberg, Professor Steven Bellman
Published in: Proceedings of the National Academy of Science (PNAS)
Dr Cameron Bracken Dr Cameron Bracken and his team explored the process of Epithelial-Mesenchymal Transition (EMT) that can be turned on inappropriately in cancer to enhance the invasiveness and chemo-resistance of cancer cells.
Article: Combinatorial Targeting by MicroRNAs Co-ordinates Post-transcriptional Control of EMT;
Authors: Joseph Cursons, Katherine A. Pillman, Kaitlin G. Scheer, Philip A. Gregory, Momeneh Foroutan, Soroor Hediyeh-Zadeh, John Toubia, Edmund J. Crampin, Gregory J. Goodall, Cameron P. Bracken, Melissa J. Davis;
Published in: Cell Systems, July 2018
Dr Tasha Stanton's research found, how stiff your back feels does not necessarily relate at all to how stiff your back actually is, but relates to how protective we are of our backs.
Article: Feeling stiffness in the back: a protective perceptual inference in chronic back pain;
Authors: Tasha R. Stanton, G. Lorimer Moseley, Arnold Y. L. Wong & Gregory N. Kawchuk;
Published in: Scientific Reports 2017
Professor Doug Brooks and his team have identified a protein called NOX2 oxidase, which is responsible for making reactive oxygen species within cells and this is activated by viruses, including influenza and the rhinovirus, also known as the common cold.
Article: Endosomal NOX2 oxidase exacerbates virus pathogenicity and is a target for antiviral therapy;
Authors: Eunice E. To, Ross Vlahos, Raymond Luong, Michelle L. Halls, Patrick C. Reading, Paul T. King, Christopher Chan, Grant R. Drummond, Christopher G. Sobey, Brad R. S. Broughton, Malcolm R. Starkey, Renee van der Sluis, Sharon R. Lewin, Steven Bozinovski, Luke A. J. O’Neill, Tim Quach, Christopher J. H. Porter, Doug A. Brooks, John J. O’Leary and Stavros Selemidis;
Published in: Nature Communications 2017
Dr George Chen explains how he and his team have combined the qualities of optical microfiber technology and polyelectrolyte multilayer coatings to achieve super fast sensors for humidity control in meteorology, agriculture, smart buildings that regulate its ambient conditions, food storage, medical diagnostics and manufacturing.
Article: Ultra-fast hygrometer based on U-shaped optical microfiber with nanoporous polyelectrolyte coating;
Authors: George Y. Chen, Xuan Wu, Yvonne Qiongyue Kang, Li Yu, Tanya M. Monro, David G. Lancaster, Xiaokong Liu & Haolan Xu;
Published in: Scientific Reports 2017
Dr Vijay Suppiah explains the role of a patient's genetic makeup in determining treatment response in chronic hepatitis C infections.
Article: Zinc is a potent and specific inhibitor of IFN-13 signalling;
Authors: Scott A. Read, Kate S. O’Connor, Vijay Suppiah, Chantelle L. E. Ahlenstiel, Stephanie Obeid, Kristina M. Cook, Anthony Cunningham, Mark W. Douglas, Philip J.Hogg, David Booth, Jacob George & Golo Ahlenstiel;
Published in: Nature Communications 2017
Professor Ajayan Vinu explains how clean energy can be generated simply with the help of water and sun light.
Published in: Angewandte Chemie International Edition, April 2017
Professor Ina Bornkessel-Schlesewsky provides the first demonstration that, in natural stories, predictions concerning the probability of remention of a protagonist at a later point are processed in the dorsal auditory stream.
Authors: Katerina Danae Kandylaki, Arne Nagels, Sarah Tune, Tilo Kircher, Richard Wiese, Matthias Schlesewsky, and Ina Bornkessel-Schlesewsky
Published in: The Journal of Neuroscience, November 30, 2016
Dr Siobhan Banks investigates effectiveness of a ‘split sleep schedule’ for shift workers.
Published in: Chronobiology International, 2014
Prof Adrian Esterman explains a patient management system for atrial fibrillation which kept patients out of hospital and was cost effective for the health system.
Published in: Lancet, 2014
Associate Professor Drew Evans discusses how important polymers are to everyday lives and how recent research shows how some polymers can conduct electricity.
Published in: Nature, 2013
Professor Timothy Olds examines how changes in children's sleep affect their overall health and wellbeing, in that it's not just lack of sleep that affects them but also what time they go to sleep.
Published in: International Journal of Obesity, 2013