Dr Ida Owens
Section on Genetic Disorders of Drug Metabolism, Human Genetics Branch, National Institute of Child Health and Human Development, Bethesda, MD, USA
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Email: owens@helix.nih.gov |
| Owens IS. Genetic regulation of UDP-glucuronosyltransferase induction by polycyclic aromatic compounds in mice. Co-segregation with aryl hydrocarbon (benzo(alpha)pyrene) hydroxylase induction. J Biol Chem 252(9):2827-1833 (1977) Abstract |
| Owens IS, Mackenzie PI. Differential induction and glycosylation of UDP-glucuronosyltransferase. Biochem Soc Trans 12(1):54-55 (1984) Abstract |
| Ritter JK, Crawford JM, Owens IS. Cloning of two human liver bilirubin UDP-glucuronosyltransferase cDNAs with expression in COS-1 cells. J Biol Chem 266(2):1043-1047 (1991) Abstract |
| Ritter JK, Chen F, Sheen YY, Tran HM, Kimura S, Yeatman MT, Owens IS. A novel complex locus UGT1 encodes human bilirubin, phenol, and other UDP-glucuronosyltransferase isozymes with identical carboxyl termini. J Biol Chem 267(5):3257-3261 (1992) Abstract |
| Ritter JK, Yeatman MT, Ferreira P, Owens IS. Identification of a genetic alteration in the code for bilirubin UDP-glucuronosyltransferase in the UGT1 gene complex of a Crigler-Najjar type I patient. J Clin Invest 90(1):150-155 (1992) Abstract |
| Ciotti M, Yeatman MT, Sokol RJ, Owens IS. Altered coding for a strictly conserved di-glycine in the major bilirubin UDP-glucuronosyltransferase of a Crigler-Najjar type I patient. J Biol Chem 270(7):3284-3291 (1995) Abstract |
| Mackenzie PI, Owens IS, Burchell B, Bock KW, Bairoch A, Belanger A, Fournel-Gigleux S, Green M, Iyanagi T, Lancet D, Louisot P, Magdalou J, Roy Chowdhury J, Ritter JK, Schachter H, Tephly TR, Tipton KF, Nebert DW. The UDP glycosyltransferase gene superfamily: Recommended nomenclature update based on evolutionary divergence. Pharmacogenetics 7, 255-269 (1997) Abstract |
| Ciotti M, Cho JW, George J, Owens IS. Required buried alpha-helical structure in the bilirubin UDP-glucuronosyltransferase, UGT1A1, contains a nonreplaceable phenylalanine. Biochemistry 37(31):11018-11025 (1998) Abstract |
Last revised : 11th October, 1998
URL is http://www.unisa.edu.au/pharm_medsci/owens.htm