Dr Dusan Losic
Contact Details
Tel: +61 8 8302 6862
Fax: +61 8 8302 3683
Email: dusan.losic@unisa.edu.au
Position
Senior Research Fellow
Qualifications
BSc Novi Sad, Serbia PhD Flinders
Background
Dusan Losic has broad research interests that interface physical chemistry, electrochemistry, analytical chemistry and surface chemistry. His PhD at Flinders University (1999-2002) involved the study of self-assembled monolayers on gold and their application for building complex nanoarchitectures and biosensing devices. After completing
his PhD he joined the Neurochemistry Research Group at Monash University
(Dept of Biochemistry) as a Postdoctoral Research Fellow to study the role of surface/interface interactions that cause the conformational changes and aggregations of Ab amyloids in relation to Alzheimer’s disease. He completed his postdoctoral experience at Flinders University working on the diatom project (ARC) where he pursued his research interest in bioinspired materials and nanostructures based devices, in particular related to molecular separation and
biosensing.
Research Interests
Dusan's research interests are in the field of nanoscience and
nanotechnology, encompassing several disciplines such as chemistry,
material science, engineering, biology and medicine, where his expertise
in electrochemistry and surface chemistry has been applied in addressing
important issues in nano scale fabrication, molecular separation,
self-assembly, and biosensing. His current research is focused on
developing electrochemical nanofabrication approaches to design new
nanoporous materials with unique structural, chemical, catalytic, and
optical properties and their applications for building new devices and
technologies for molecular separation, sensing/biosensing, drug
delivery, catalysis and energy storage/conversion.
Major Research Projects
ARC (ARF)-Discovery: Engineered nanotube membranes for molecular
separation and biosensing
ARC- Discovery: Periodic nano-ratchets: a new paradigm for biomolecule
separation
ARC-Linkage: Advanced nanoscale materials engineered from diatomaceous
earth
ARC-Linkage: Microchip Impedance Biosensor for Biomedical Diagnostics
ARC-International Linkage: Combining the soft with the hard: the
assembly of artificial membranes on porous semi-conductors (Flinders
University, University of Barcelona, University of Chicago, Institute of
Charles Gerhardt Montpelier – CNRS)
Selected Journal Papers
S. Simovic, D. Losic, Ordered mesoporous materials for drug delivery
applications, Book chapter, ed. Frank Columbus, Nova Science Publisher,
New York, 2010, (in press)
S. Simovic, D. Losic, K. Vasilev, Controlled drug release from
mesoporous materials by plasma polymer deposition, Chemical
Communications 2010, DOI: 10.1039/ b919840g (in press)
Abdul. Md Jani, I. M. Kempson, D. Losic, N. H. Voelcker, dress in
layers: layering surface functionalities in nanoporous aluminium oxide
membranes, Angew. Chem., Int. Ed. 2010 (under review)
Reza E. Sabzi, K. Kant, D.Losic, Electrochemical synthesis of Ni
hexacyanoferrate nanoarrays with dots, rods and tubes morphology using
porous alumina template, Electrochimica acta, 2010,
10.1016/j.electacta.2009.10.075 (in press)
K. Vasilev, Z. Poh, K. Kant, J. Chan, A, Michelmore, D. Losic, Tailoring
the surface functionalities of titania nanotube arrays, Biomaterials
2010, 31, 532-540
D. Losic, J.G. Mitchell, N.H. Voelcker, Diatomaceous lessons in
nanotechnology and advanced materials, Advanced Materials, 2009, 21,
1-12, (journal cover)
D. Losic, M. Lillo, D. Losic Jnr., Porous alumina with shaped pore
geometries and complex pore architectures fabricated by cyclic
anodization, Small, 2009, 5, 1392-1397 (journal cover)
D. Losic, S. Simovic, Self-ordered nanopore and nanotube platforms for
drug delivery applications, Expert Opinion in Drug Delivery, 2009, 6,
1363-1380 (invited review)
A. M. Md Jani, E. J. Anglin, S. J.P. McInnes, D. Losic, J. G. Shapter,
N. H. Voelcker, Fabrication of nanoporous anodic alumina membranes with
layered surface chemistry, Chemical Communications, 2009, 3062-3064.
D. Losic, D. Losic Jnr, Preparation of Porous Anodic Alumina with
Periodically Perforated Pores, Langmuir, 2009, 25, 5426-5431
Gordon, R., D. Losic, M.A. Tiffany & S.S. Nagy, F.A.S. Sterrenburg, The
Glass Menagerie: diatoms for novel applications in nanotechnology,
Trends in Biotechnology, 2009, 27, 116-127. (Invited review)
K. Krishna, D. Losic, A simple approach for synthesis of TiO2 nanotubes
with through-hole morphology, Physica Status Solidi RRL, 2009, 3, No. 5,
139–141
L. Velleman, G. Triani, P. J. Evans, J. G. Shapter, D. Losic, Structural
and chemical modification of porous alumina membranes, Microporous and
Mesoporous Materials, 2009, 126, 87-94
M. Lillo, D. Losic, Pore opening detection for controlled dissolution of
barrier oxide layer and fabrication of nanoporous alumina with
through-hole morphology, Journal of Membrane Science, 2009, 327, 11-17.
L. Velleman, J.G. Shapter, D. Losic, Gold nanotube membranes
functionalised with fluorinated thiols for selective molecular
transport, Journal of Membrane Science, 2009, 328, 121-126.
M. Lillo, D. Losic, Ion-beam pore opening of porous anodic alumina: the
formation of single nanopore and nanopore arrays, Materials Letters,
2009, 63, 457-460.
D. Losic, M. A. Cole, B. Dollmann, K. Vasilev, H. J. Griesser, Surface
modifications of nanoporous alumina membranes by plasma polymerisation,
Nanotechnology, 2008, 19, 245704 (7 pg)
D. Losic, J. G. Mitchell, R. Lal, N. H. Voelcker, Rapid prototyping of
micro- and nanoscale patterns by replica moulding from diatom biosilica,
Advanced Functional Materials, 2007, 1, 2439-2446.
D. Losic, K. Short, R. Lal, J. Mitchell, N. H. Voelcker, AFM
nanoindentations of Diatom Biosilica surface, Langmuir, 2007, 23,
5014-5021.
J. J. Gooding, A. Chou, J. Liu, D. Losic, J. G Shapter, D. B. Hibbert,
The effects of the lengths and orientations of single-walled carbon
nanotubes on the electrochemistry of nanotube-modified electrodes,
Electrochemistry Communications, 2007, 9, 1677-1683.
J. Yu, M. D. Losic, Marshall, T. Bocking, J. J. Gooding, J. G. Shapter,
Preparation and Characterization of an Aligned Carbon Nanotube Array on
Silicon (111) Surface, Soft Matter, 2006, 2, 1081-1088.
M. A. Cole, H. Thissen, D. Losic, N. H. Voelcker, A new approach to the
reduction of non-specific protein adsorption on conductive substrates,
Surface Science, 2007, 601, 1716-1725.
D. Losic, G. Triani, P. Evans, A. Atanacio, J. Mitcheli, N. H. Voelcker,
Controlled pore structure modification of diatoms by atomic layer
deposition of TiO2, Journal of Materials Chemistry, 2006, 16, 4029-4034.
(journal cover)
D. Losic, L. L. Martin, A. Mechler, M.-I. Aguilar, D. H. Small, High
resolution scanning tunnelling microscopy of the β-amyloid protein
(Aβ1-40) of Alzheimer’s disease suggests a novel mechanism of oligomer
assembly, Journal of Structural Biology, 2006, 155, 104-110.
S. S. Mok, D. Losic, C. J. Barrow, B. J. Turner, C. L. Masters, L. L.
Martin, D. H. Small, The β-amyloid peptide of Alzheimer's disease
decreases adhesion of vascular smooth muscle cells to the basement
membrane, Journal of Neurochemistry, 2006, 96, 53-64.
D. Losic, G. Rosengarten, J. G. Mitchell, N. H. Voelcker, Pore
architecture of diatom frustules: potential nanostructured membranes for
molecular and particle separations, Journal of Nanoscience and
Nanotechnology, 2006, 6, 982-989.
D. Losic, J. G. Mitchell, N. H. Voelcker, Complex gold nanostructures
derived by templating from diatom frustule, Chemical Communications,
2005, 4905-4907 (journal cover)
D. Losic, J. G. Shapter, J. Mitchell, N. H. Voelcker, Fabrication of
gold nanorod arrays by templating from porous alumina, Nanotechnology,
2005, 16, 2275-2281.
D. Losic, M. Cole, H. Thissen, N. H. Voelcker, Ultrathin polytyramine
films by electropolymerisation on highly doped p-type silicon
electrodes, Surface Science, 2005, 584, 245-247.
M. Snow, P. Self, D. Losic, J. G. Shapter, A. Pring, The origin of the
body colour of pearls in iridescence from nano-composite structures of
the nacre, American Mineralogist, 2004, 89, 1353-1358.
D. H. Small, D. Losic, L. L. Martin, B. J. Turner, A. Friedhuber, M. I.
Aguilar, New approaches to Alzheimer’s disease therapeutics,
International Union of Biochemistry and Molecular Biology, IUBMB
Letters, 2004, 56, 203-208. (critical review)
L. R. Fodero, S. S. Mok, D. Losic, L. L. Martin, M. I. Aguilar, C. J.
Barrow, B. G. Livett and D. H. Small, α7-Nicotinic acetylcholine
receptors mediate an Aβ1-42 induced increase in the level of
acetylcholinesterase in primary cortical neurons, Journal of
Neurochemistry, 2004, 88, 1186-1193.
G. M. J. A. Klug, D. Losic, S. S. Subashinghe, L. L. Martin, M-I.
Aguilar, D. H. Small, Aβ oligomers induced by metal ions and acid pH are
distinct from those generated by spontaneous ageing at neutral pH,
European Journal of Biochemistry (FEBS journal), 2003, 270, 4282 - 4293.
J. J. Gooding, R. Wibowo, J. Liu, W. Yang, D. Losic, S. Orbons, F. J.
Mearns, J. G. Shapter, D. B. Hibbert, 2003. Protein Electrochemistry
using Aligned Carbon Nanotubes Electrode Arrays, Journal of American
Chemical Society, 2003, 125, 9006-9007.
D. Losic, J. J. Gooding, M. Zhao, J. G. Shapter, Which Parameters
Affects the Response of the Channel Biosensor, Electroanalysis, 2003,
15, 183-190. (feature article)
D. Losic, J. G. Shapter, J. J. Gooding, Integrating Polymers with
Alkanethiol Self-Assembled Monolayers: Blocking SAM Defects with
Electrochemical Polymerisation of Tyramine, Electrochemistry
Communications, 2002, 4, 953-958.
D. Losic, J. G. Shapter, J. J. Gooding, Scanning Tunnelling Microscopy
studies of Glucose Oxidase on Gold, Langmuir, 2002, 18, 5422-5428.
D. Losic, J. J. Gooding, J. G. Shapter, Influence of Surface Topography
on Alkanethiols SAMs Assembled from Solution and by Microcontact
printing, Langmuir, 2001, 17, 3307-3316.
D. Losic, J. G. Shapter, J. J. Gooding, Atomically Flat Gold for
Biomolecule Immobilisation and Imaging, Australian Journal of Chemistry
2001, 54, 643-648.
D. Losic, J. J. Gooding, J. G. Shapter, D. B. Hibbert, K. Short, The
Influence of the Underlying Gold Substrate on Glucose Oxidase Electrode
Fabricated Using Self-Assembled Monolayers, Electroanalysis, 2001, 13,
1385-1393.
D. Losic, J. G. Shapter, J. J. Gooding, Concentration Dependence in
Microcontact Printing of Self-assembled Monolayers (SAMs) of
Alkanethiols, Electrochemistry Communications, 2001, 3, 722-726.
J. J. Gooding, P. Erokhin, D. Losic, W. R. Yang, V. Policarpio, J. Q.
Liu, F. M. Ho, M. Situmorang, D. B. Hibbert, J. G. Shapter, Parameters
Important in Fabricating Enzyme Electrodes Using Self-Assembled
Monolayers of Alkanethiols, Analytical Sciences, 2001, 17, 3-9.