The Experimental Therapeutics Laboratory is a collaborative venture between scientists from the Sansom Institute for Health Research (University of South Australia), the Hanson Institute, the Cancer Clinical Trials Unit (Royal Adelaide Hospital Cancer Centre).
We perform basic, translational and clinical research that aims to improve chronic and acute health outcomes by exploring novel immunotherapeutic approaches to treat and prevent cancer, allergy and other diseases including chronic and acute infections and uncontrolled inflammation in sepsis and the body’s response to biomaterial implants. Our expertise exploits the specificity and power of the immune system to design, develop, and implement cutting edge approaches to new therapeutic and diagnostic agents.
Industry links, experience and clinical expertise ensure that our research has a strong likelihood of generating applications for potential commercialisation and improved therapeutic outcomes for patients.
Current Competitive Grants and Fellowships
ARC Discovery Grant DP15104212 ‘Surface engineered biomaterials to control inflammation’. K. A. Vasilev and J. D. Hayball. Awarded $330,000 for 2015-17.
Ilhan Food Allergy Foundation ‘Modulating antibody receptor signalling to treat peanut allergy’. J. D. Hayball, A. Flies, W. Smith and B. Tao. Awarded $45,000 for 2015-16.
Channel 7 Children’s Research Foundation Grant ID151079 ‘Modulating Fc receptor signalling to treat and prevent peanut allergy’. J. D. Hayball, A. Flies, W. Smith and B. Tao. Awarded $75,000 for 2015-16.
China-Australia Centre for Health Research Grant. ‘Development of a novel viral-vector based human papilloma virus therapeutic vaccine’. J. D. Hayball, L. Liu and X. Wang. Awarded $20,000 for 2015-16.
Sansom Institute for Health Research Grant .New biomaterials for improved tissue implant performance’. J. D. Hayball and K. Vasilev. Awarded $50,000 for 2014.
Tasmanian Devil Research Advisory Committee Grant ‘Translating successful human cancer immunotherapy techniques to veterinary medicine using naturally transmissible tumours as model systems’ .A. Flies, G. Woods and J. D. Hayball. Awarded $20,000 for 2014-15.
Morris Animal Foundation Fellowship ‘Investigation of cancer immunotherapy for the Tasmanian devil facial tumor disease’. A. Flies, G. Woods and J. D. Hayball. Awarded $200,000 for 2014-16 (MAF, UniSA and UTas).
Sansom Institute for Health Research Grant ‘Translating successful human cancer immunotherapy techniques to veterinary medicine using naturally transmissible tumours as model systems’. A. Flies, G. Woods and J. D. Hayball. Awarded $10,000 for 2014-15.
Robinson Research Institute Innovation Seed Funding Program ‘The development of a new passive immunotherapeutic for the treatment and prevention of sepsis in mouse neonates’. K. R. Diener, J. D. Hayball, M Stark, and N Hodyl. Awarded $25,000 for 2014-15.
AusIndustry Entrepreneur Development “Researchers-in-Business’ Scheme ‘New vaccines for infectious diseases, allergy and cancer’. J. D. Hayball and P. Howley Awarded $150,000 for 2014-15 (Sementis Ltd and UniSA).
Sementis Ltd. ‘New vaccines for infectious diseases, allergy and cancer’. J. D. Hayball, Awarded $4,000,000 for 2012-16.
Sementis Ltd. ‘A new vaccine Chikungunya virus infections’. J. D. Hayball. Awarded $180,000 for 2012-15.
Premiers Science Fund Collaboration Pathways Program ‘Development of diagnostic and prognostic devices and advanced biomaterials for the treatment of kidney disease’. K. Vasilev, J. D. Hayball, J. Gleadle, P. Majewski, H. Griesser, M. Michael. Awarded $600,000 for 2012-15 (SAGov and UniSA).
ARC Linkage Project Grant LP120100606. ‘The development of a potent new passive immunotherapeutic for the treatment and prevention of bacterial sepsis and septic shock'. JD Hayball, T Kuchel and M Chapman. Awarded $333,000 for 2012-14 (ARC and Industry Partners).
NHMRC Project Grant, Application ID 1020984. 'The consequences of innate immune inflammatory responses during early pregnancy and their effect on reproductive outcomes'. KR Diener. Awarded $326,175 for 2012-2014.
NHMRC Training Fellowship, Application ID 1012386. ‘Innate anti-viral effector responses and adverse reproductive outcomes’. KR Diener. Awarded $290,032 for 2011-2014.
International Patent Application No PCT/AU2014/000791 “Analyzing intracellular calcium flux in cells including T cells”. University of South Australia and Adelaide Research and Innovation Pty Ltd. Lead inventor: J.D. Hayball.